Coffee May Reduce Risk of Colon Cancer

Coffee May Reduce Risk of Colon Cancer

If you are a coffee lover you have one more reason for your daily mug: a new study says that drinking coffee may reduce risk of colon cancer.

Prerequisite for that research was the fact that coffee contains several bioactive compounds relevant to colon physiology.

The team investigated the association between coffee consumption and risk of colorectal cancer in northern Israel. Two groups of people were involved:

  1. Case group – 5,145 male and female patients diagnosed with colorectal cancer within the past 6 months
  2. Control group – 4,097 people with no history of colorectal cancer.

The following indexes were collected and analyzed:

  • daily consumption of coffee
  • type of coffee
  • consumption of other liquids
  • family history of cancer
  • diet
  • physical activity
  • smoking
  • cancer site (colon and rectum)
  • ethnic subgroup (Ashkenazi Jews, Sephardi Jews, and Arabs)

The research team came to the conclusion that coffee consumption may be inversely associated with risk of colorectal cancer in a dose–response manner.

Consumption of one to two servings of coffee per day was associated with a 26% reduction in the odds of developing colorectal cancer after adjustment for known risk factors. If the number of coffee servings was more than 2.5 per day, the colorectal cancer risk decreased up to 50% regardless of what flavor or form of coffee people drank. Moreover, this decreased risk was for both caffeinated and decaffeinated coffee, meaning that caffeine alone is not responsible for coffee’s protective properties.

The senior author of this study was Stephen Gruber, M.D., Ph.D., director of the University of Southern California (USC) Norris Comprehensive Cancer Center with the assistance of a research team led by Gad Rennert, M.D., Ph.D., director of the Clalit National Israeli Cancer Control Center in Haifa, Israel.

You can find the paper titled “Coffee Consumption and the Risk of Colorectal Cancer” in the April 2016 issue of Cancer Epidemiology, Biomarkers & Prevention, which is published by the American Association of Cancer Research.

There have been a growing number of scientific studies suggesting that drinking as much as four or more cups of coffee per day might lower the risk of gastrointestinal cancers, including liver cancer, type 2 diabetes and even dementia.

Enjoy your cup of coffee, or two, or three, or four … or more every day!


  • (Coffee Consumption and the Risk of Colorectal Cancer)


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